ECTS credits ECTS credits: 3
ECTS Hours Rules/Memories Student's work ECTS: 51 Hours of tutorials: 3 Expository Class: 9 Interactive Classroom: 12 Total: 75
Use languages Spanish, Galician
Type: Ordinary subject Master’s Degree RD 1393/2007 - 822/2021
Departments: Microbiology and Parasitology
Areas: Microbiology
Center Faculty of Biology
Call: Second Semester
Teaching: With teaching
Enrolment: Enrollable | 1st year (Yes)
Aims and Objectives
It is intended that the student will be able to:
- To know and apply the tools of formulation, design and preparation of new vaccines and immunization strategies.
- To know, develop and apply prevention and control strategies.
- Know current regulations regarding products used in the treatment of diseases in aquaculture, treatment and disposal of waste.
Theory Themes
Theme 1.- Prevention of infectious diseases. General measures. Vaccination: basic concepts. Types of vaccines and routes of administration. Interactive effects of antigens. Vaccination strategies. 1,0 h
Theme 2.- Development of bacterial vaccines. Design of traditional vaccines: criteria for the selection of antigens. Methods of production and inactivation of vaccines. Limitations in the production of vaccines according to the traditional model. New strategies in the development of bacterial vaccines and immunization protocols. 1,5 h
Theme 3.- Development of viral vaccines. Production of attenuated and inactivated viral vaccines. Limitations in the production of vaccines according to the traditional model. New generation vaccines and immunization protocols. 1,0 h
Theme 4.- Law on medicinal products. Regulations for the control of the quality and sterility of vaccines for aquaculture. Regulations for the evaluation of the efficacy and safety of vaccines for aquaculture. Sanitary registers. Patents and Legislation. 1,0 h
Theme 5.- Sanitary and Hygiene Control. General hygiene measures. Disinfection. Physical and chemical treatments. Criteria for the choice of disinfection methods. Search and evaluation of disinfectant substances. Regulations on waste treatment and disposal. 1,0 h
Theme 6.- Biological methods for the control of infectious diseases. Phagotherapy and enzibiotics. Probiotics. Synthetic siderophores conjugated with antibiotics and interception of quorum sensing. 0,75 h
Theme 7.- Control of non-infectious diseases in aquaculture. Control of infectious diseases. Criteria for the selection of antimicrobial agents and methods of application. Responsible use of pharmaceuticals in aquaculture. 0.75 h
Theme 8.- Law on medicinal products. Legislation on therapeutics and maximum residue limit (MRLs). 1,0 h
Practical topics
Practice 1.- In vitro evaluation of the efficacy of antimicrobial agents and disinfectants. 2,0 h
Practice 2.- Evaluation of the efficacy and safety of vaccines: "in vivo" trials and analysis and interpretation of the results. 1,5 h
Practice 3.- Determination of critical control points in aquarium systems and determination of microbiological parameters- 2.0 h
Practice 4.- Search for information on patents, treatments, vaccines and legislation 0.5h
• Buller, N. B. 2004. Bacteria from fish and other aquatic animals, a practical identification manual. CAbi Publishing, UK.
• Buller, N. B. 2014. Bacteria and Fungi from Fish and Other Aquatic Animals: A Practical Identification Manual, 2nd Edition. CAbi Publishing, UK.
• Iwama, G. & Nakanishi, T. 1996. The fish immune system. Organism, pathogen, and environment. Academic Press.
• Gudding, R., Lillehauug, A., Midtlyng, P. 1996. Fish Vaccionology. Devolopments in Biological Standardization. Vol. 90. Karger.
• Otero Casal, A., Muñoz Crego, A., Benárdez Hermida, M.I. Fábregas, J 2004.Quorum sensing: el lenguaje de las bacterias.
Editorial Acribia, Zaragoza, España. 140 pp.
• Brodgen, K.A., J.A. Roth, T.B. Stanton. 2000. Virulence mechanisms of bacterial pathogens. ASM Press.
• Waksman, G., M. Caparon, S. Hultgren. 2005. Structural Biology of Bacterial pathogenesis. ASM Press.
• Huet, M. 1998. Tratado de Piscicultura. 3ª edición. Ediciones Mundi-Prensa.
• Treves-Brown, K.M. 2000. Applied Fish Pharmacology. Aquaculture Series 3. Kluwer Academia Publishers
• Noga, E.J. 2000. Fish Disease. Diagnosis and Treatment. Iowa State University Press.
Bibliografía complementaria
- Austin, B. y Austin, D.A. (2016). Bacterial fish pathogens: disease of farmed and wild fish. 6ª ed. Chiestester,Uk: Springer.doi: 10.1007/978-3-319-32674-0.
- Buller, N.B. 2014. Bacteria and Fungi from fish an other Aquatic Animals. A Practical identification manual. 2ª ed. Cabi. Publishing London, UK,.
- Flemming, D. O., D. L. Hunt (ed). (2000). Biological safety. Principles and Practices, 3rd Ed. ASM Press.
- Flint, S. J.. L. W. Enquist, V.R. Racaniello, A M. Skalka. (2003). Principles of Virology: Molecular Biology, Pathogenesis, and Control of animal Viruses. 2nd Ed. ASM Press.
- Gudding, R., A. Lillehaugh, O. Evensen. (2014).Fish vaccination. John Wiley & Sons, Ltd.
- Inglis, V. R. J. Roberts & N. R. Bromage. (1993). Bacterial Diseases of Fish. BlacwellScientificPublications.
- Ministerio de Agricultura Pesca y Alimentación (Ed). (2000). El Libro Blanco de la Acuicultura en España.
- Schlotfeldt, H. J., D. J. Alderman. (1995). What should I do? A practical guide for the Fresh water Fish Farmer. European Association of Fish Pathologists Ed.
Recursos WEB
https://www.woah.org/es/que-hacemos/normas/codigos-y-manuales/
http://www.Fishbase.org/
General competences:
- CG03- Evaluate the importance of multidisciplinary analysis and the relationship between knowledge to solve problems and to analyze critical points.
- CG06- Search and consult information sources and databases; analyze and synthesize documents.
- CG08- Promote the use of foreign languages.
- CG09- To apply critical, logical and creative thinking.
Specific competences.
- CE05- Diagnosis, prevention and control of diseases.
Basic skills.
- CB02- that the students know how to apply the acquired knowledge and their capacity to solve problems in new or unknown environments within broader (or multidisciplinary) contexts related to their area of study;
- CB03- that students are able to integrate knowledge and face the complexity of formulating interpretations and judgments from information that is often incomplete, include reflections on social and ethical responsibilities linked to the resolution of specific problems.
Cross-cutting competencies
- CT4 - Dexterity in the search, analysis and interpretation of diverse sources of information in different languages (mainly English).
Theoretical classes: They will have an approximate duration of 50 minutes. The exhibition method will be used, supported by multimedia presentations (power point, videos and connections to interesting web resources). At the beginning of the course, the student will receive a script of each of the topics with the recommended bibliography.
Personalized tutorials for the direct support to the students.
Seminars: these are complementary to the theoretical classes, and are intended to contribute to consolidating the knowledge acquired in the theoretical classes.
Practices: 1 day at USC, Campus Vida
Plant visit (subject to availability of funding)
Theoretical exam [Theoretical exam (40-60% of final grade) Description: multiple-choice exam, although the option of a question to be developed is retained].
Description: Attendance (0-20); continuous assessment (0-20) and notebook presentation (0-20).
Attendance and participation (0-15%) Use of the talks [Attendance and summary] and participation in other activities; the score in this section, if not applicable, will be added to the previous one].
Non-attendance hours: 51
Attendance at classes and titories.
Consultation of recommended bibliography.
Participation in classes
It is recommended to have passed the subject of Pathology in Aquaculture. It is also advisable to complement the subjects of Prevention and Control and Epidemiology
Maria Isabel Santos Rodriguez
Coordinador/a- Department
- Microbiology and Parasitology
- Area
- Microbiology
- Phone
- 881816028
- ysabel.santos [at] usc.es
- Category
- Professor: University Professor
Beatriz Magariños Ferro
- Department
- Microbiology and Parasitology
- Area
- Microbiology
- Phone
- 881816914
- beatriz.magarinos [at] usc.es
- Category
- Professor: University Professor