ECTS credits ECTS credits: 6
ECTS Hours Rules/Memories Hours of tutorials: 3 Expository Class: 27 Interactive Classroom: 21 Total: 51
Use languages Spanish, Galician
Type: Ordinary Degree Subject RD 1393/2007 - 822/2021
Departments: Biochemistry and Molecular Biology
Areas: Biochemistry and Molecular Biology
Center Faculty of Biology
Call: Second Semester
Teaching: With teaching
Enrolment: Enrollable
The main objective of this course is that students have a current and global view on the functioning of the immune system and that they know the fundamental notions of the immune response, the cells and molecules that make up the immune system and the existing communication and cooperation mechanisms between the different cell types. For this purpose, specific objectives are set:
-Number the cells and tissues of the immune system.
-Identify the bases of the immune response and its regulation.
-Differentiate between the causes of immune diseases.
-Number the main methods that use antibodies for the detection and quantification of biomolecules and interpret the results of immunoassays.
-Identify the applications of immunobiotechnology.
-Make valuations of the specific and non-specific immune response.
Lectures:
Thematic blocks
1- Properties and generalities of immune responses: Introduction to Immunology. The immune response. Tissues and cells of the immune system.
2- Molecules and cells that interact with the Antigen: Immunoglobulins. Histocompatibility. Antigen processing. T lymphocyte receptor.
3- Innate immune response: Receptors, components. Inflammatory answer.
4- Adaptive immune response and effector mechanisms: Maturation and activation of T and B lymphocytes; production of antibodies. Effector Mechanisms of Immune Responses: Cytokines and Their Receptors
5- Immunity against infections: Immunity against infectious agents: viruses, bacteria and parasites.
6- Immunological Tools: Laboratory techniques, alterations and evaluation of immunity.
The development of the thematic blocks will take approximately 3 hours for blocks 1 and 5, 4 hours for block 3, and 5 hours for blocks 2 and 6 and 7 hours for block 4.
Laboratory.
The proposed experiments are conceptually correlative to the theoretical themes of the subject. According to the hours established for the subject, the students will have to carry out a series of experimental essays and / or computer tools, collect the results obtained and analyze them properly to answer the questions and exercises set out in the practice script.
-Recognition of the component cells of the immune system. Determination of cell viability.
-Laboratory methods that use antibodies (ELISA).
-Determination and study of lymphocyte subpopulations by Flow Cytometry.
-Electrophoresis of plasmatic proteins.
Seminars
According to the hours established for the subject, it will consist of 3 seminars with a total of 7 hours. The objectives are to apply and reinforce through questions, practical and / or clinical cases, the knowledge developed in the lectures. Aiming at the knowledge of the methods to study T and B lymphocyte responses, the manipulation of the immune response and the development of immunobiotechnology.
Tutorials
According to the hours established for the subject, the tutorials oriented to the resolution of the particular doubts generated in the expository and interactive classes will be carried out. The objective is to clarify the basic concepts that govern the functioning of the immune system and its application in pathological cases and / or their therapy.
Básic:
- Abul K. Abbas, Andrew H. Lichtman, Shiv Pillai, 2022, Inmunología celular y molecular, 10ª ed.,Barcelona:Elsevier, cop. 2022.
- Jenni Punt, Sharon A. Stranford ; Edición 2020, Kuby inmunología 8ª ed. McGraw Hill Interamericana.
- Abbas, A.K., Lichtman, A.H. y Pillai, S., 2012. Inmunología celular y Molecular. [Recurso electrónico]. ed. Barcelona: Elsevier. Acceso restrinxido a usuarios USC <https://www.dawsonera.com/terms/show?dest=https%3A%2F%2Fwww.dawsonera.c…>.
- Abbas, Abul K. Andrew H. Lichtman, Shiv Pillai, 2020, Inmunología básica : funciones y trastornos del sistema inmunitario, 6ª ed. Barcelona : Elsevier, cop.
- Regueiro González, J.R. et al., 2022. Inmunología: biología y patología del sistema inmunitario. 5ª Edición, Madrid: Editorial Médica Panamericana.
Complemmentary:
- K. Murphy, C. Weaver Inmunobiology Janeway, 9ª edición 2017, Garlan science.
- Delves, P.J. et al., 2014, Inmunología: fundamentos., ed. Buenos Aires: Editorial Médica Panamericana.
- Leonardo Fainboim, Jorge Geffner 2011, Introducción a la inmunología humana, Edición 6ª ed., Buenos Aires : Panamericana, cop.
Knowledge/contents: Con01, Con02, Con05
Skills/skills: H/D01, H/D02, H/D03, H/D04, H/D09, H/D11, H/D12
Competencies: Comp01, Comp02, Comp03, Comp04, Comp05
Lectures, in which the concepts of the subject will be explained, with the support of audiovisual and computer media, attending directly to all the doubts and clarifications raised by the students. The help material prepared to facilitate the monitoring and understanding of the topics (which is a summary of the topics explained) is provided to you in the virtual campus of the USC corresponding to the subject.
In the interactive seminar classes, applications of the theory will be proposed and solved, exercises, problems, simulations of clinical cases, etc. will be carried out. Active participation of students is required. It is programmed to provide them with information and complementary material (videos, web addresses, etc.) that will allow them a better understanding of the subject.
Laboratory practical classes, in which the students, following the protocols prepared for this purpose, will manage the appropriate equipment and solve practical and / or applied questions.
Tutorials guide to clarify particular doubts, provide information or guide the students, as well as to know the progress in the acquisition of knowledge.
The activities: lectures, seminars and laboratory practices are non-compulsory activities that can be evaluated. And the Final Test is a compulsory activity that can be assessed in addition to the continuous assessment.
1."The evaluation of the subject will be the same for repeaters and non-repeaters, with no notes from previous years being kept. Furthermore, the evaluation will always be the same on both occasions and will consist of the following qualifications for the parts into which the subject is divided:
1.1) Continuous evaluation (20% of the final grade), which in turn is composed of:
-Seminars (10% of the final grade). NON-OBLIGATORY EVALUABLE ACTIVITY.
-Laboratory Practices (10% of the final grade). NON-OBLIGATORY EVALUABLE ACTIVITY. Unexcused absences will result in a qualification of NOT SUITABLE. Control of attendance at in-person activities will be carried out by roll call.
1.2) Final Test (80% of the final grade). MANDATORY EVALUABLE ACTIVITY COMPLEMENTARY TO CONTINUOUS EVALUATION. It will be carried out in person and will consist of an exam with multiple choice questions, questions and exercises, related to the theoretical-practical contents of the subject.
Evaluation of learning outcomes:
-Exam: Con01, Con02, Con05.
-Seminar works/exercises: H/D01, H/D02, H/D03, H/D04, H/D09, H/D11.
-Practices: Con05, H/D12, Comp01, Comp02, Comp03, Comp04, Com05
In general, the average number of work hours for this subject is 150, of which 50 hours correspond to attendance at theoretical classes (27 hours), 14 hours of interactive laboratory classes, 7 hours of interactive seminar classes and 2 hours of tutoring in small groups and non-face-to-face 96 hours of dedication in individual study to prepare the subject.
Use of the recommended bibliography, as well as the graphic material provided by the teacher, essential for the understanding of the subject.
Reading and frequent reflection on the subject taught, necessary for the integration of knowledge in this field of science.
Interest and attention on new advances in this discipline disseminated through the media, for incorporation and discussion in classes and seminars.
The subject will have a virtual classroom on the Moodle platform. Communication with students will be done through email, the Moodle platform and / or through the MS-teams application.
“For cases of fraudulent performance of exercises or tests, the provisions of the regulations for the evaluation of the academic performance of students and the review of grades will apply.” This indicates that the fraudulent performance of any exercise or test required in the evaluation will imply the failing grade in the corresponding call, regardless of the disciplinary process that may be followed against the offending student. Considering fraudulent, among others, the completion of plagiarized work (for example, from classmates or previous courses) or obtained from sources accessible to the public without reworking or reinterpretation and without citations to the authors and sources. The distribution by different means (for example, web pages) and without the teacher's consent, of any teaching material posted in the classroom is also strictly prohibited. virtual.
Ma Del Pilar Arias Crespo
Coordinador/a- Department
- Biochemistry and Molecular Biology
- Area
- Biochemistry and Molecular Biology
- Phone
- 881816933
- pilar.arias [at] usc.es
- Category
- Professor: University Lecturer
| Tuesday | |||
|---|---|---|---|
| 16:00-17:00 | Grupo /CLE_01 | Spanish | Classroom 08. Louis Pasteur |
| Wednesday | |||
| 16:00-17:00 | Grupo /CLE_01 | Spanish | Classroom 08. Louis Pasteur |
| 05.30.2025 16:00-20:00 | Grupo /CLE_01 | Classroom 04: James Watson and Francis Crick |
| 07.14.2025 16:00-20:00 | Grupo /CLE_01 | Classroom 03. Carl Linnaeus |