Pneumococcal vaccination coverage in transplanted patients in a health area of northwestern Spain. A cross-sectional study
Authorship
A.N.G.
Master in Public Health
A.N.G.
Master in Public Health
Defense date
02.18.2025 09:00
02.18.2025 09:00
Summary
Introduction: Streptococcus pneumoniae is a bacterium that causes several infectious conditions among which invasive pneumococcal disease stands out due to its important morbimortality, mainly in immunocompromised subjects. Vaccination against this microorganism represents the main tool to reduce the probability of infection. Methods: We conducted a descriptive study to know the vaccination coverage against Streptococcus pneumoniae in patients belonging to a health area of northwestern Spain who have undergone solid organ transplantation (SOT) or hematopoietic stem-cell transplantation (HSCT) from 2017 to 2022. Subjects were selected from the “Registro de Actividad de Atención Especializada (RAE-CMBD)” using ICD-10 procedure codes, while vaccination data were extracted from the “Sistema de Información y Análisis Complejo (SIAC)”. Results: A total of 680 patients were included (649 belonging to the solid organ transplantation group and 211 belonging to the hematopoietic stem-cell transplantation group). In the first group, 326 patients (69.51%) have received the complete pneumococcal vaccination schedule (at least one dose of 13-valent conjugate vaccine and one dose of polysaccharide vaccine); in the second group, 45 patients (21.33%) have received the complete vaccination schedule (at least 3 doses of 13-valent conjugate vaccine and one dose of polysaccharide vaccine at least 3 months after the receipt of HSCT). Conclusions: Vaccination coverage against pneumococcus in transplanted patients in the healthcare area is suboptimal, fundamentally among patients with HSCT. It is necessary to take measures to raise awareness of the importance of vaccination both among transplanted patients and their health professionals, as well as to carry out a “catch up” of patients who have not correctly completed their vaccination regimen.
Introduction: Streptococcus pneumoniae is a bacterium that causes several infectious conditions among which invasive pneumococcal disease stands out due to its important morbimortality, mainly in immunocompromised subjects. Vaccination against this microorganism represents the main tool to reduce the probability of infection. Methods: We conducted a descriptive study to know the vaccination coverage against Streptococcus pneumoniae in patients belonging to a health area of northwestern Spain who have undergone solid organ transplantation (SOT) or hematopoietic stem-cell transplantation (HSCT) from 2017 to 2022. Subjects were selected from the “Registro de Actividad de Atención Especializada (RAE-CMBD)” using ICD-10 procedure codes, while vaccination data were extracted from the “Sistema de Información y Análisis Complejo (SIAC)”. Results: A total of 680 patients were included (649 belonging to the solid organ transplantation group and 211 belonging to the hematopoietic stem-cell transplantation group). In the first group, 326 patients (69.51%) have received the complete pneumococcal vaccination schedule (at least one dose of 13-valent conjugate vaccine and one dose of polysaccharide vaccine); in the second group, 45 patients (21.33%) have received the complete vaccination schedule (at least 3 doses of 13-valent conjugate vaccine and one dose of polysaccharide vaccine at least 3 months after the receipt of HSCT). Conclusions: Vaccination coverage against pneumococcus in transplanted patients in the healthcare area is suboptimal, fundamentally among patients with HSCT. It is necessary to take measures to raise awareness of the importance of vaccination both among transplanted patients and their health professionals, as well as to carry out a “catch up” of patients who have not correctly completed their vaccination regimen.
Direction
RUANO RAVIÑA, ALBERTO (Tutorships)
RUANO RAVIÑA, ALBERTO (Tutorships)
Court
MONTES MARTINEZ, AGUSTIN (Chairman)
RODRÍGUEZ FERNÁNDEZ, Mª DE LA ALMUDENA (Secretary)
VARELA LEMA, MARIA LEONOR (Member)
MONTES MARTINEZ, AGUSTIN (Chairman)
RODRÍGUEZ FERNÁNDEZ, Mª DE LA ALMUDENA (Secretary)
VARELA LEMA, MARIA LEONOR (Member)
Tobacco control measures: acceptance by the population
Authorship
J.M.M.M.
Master in Public Health
J.M.M.M.
Master in Public Health
Defense date
02.18.2025 09:20
02.18.2025 09:20
Summary
The objective is to assess the acceptability of new measures against tobacco consumption control measures in Spain through a survey of the population over 16 years of age. The measure of the prohibition of smoking inside cars in the presence of minors is the measure that has had the greatest acceptance among the participants.
The objective is to assess the acceptability of new measures against tobacco consumption control measures in Spain through a survey of the population over 16 years of age. The measure of the prohibition of smoking inside cars in the presence of minors is the measure that has had the greatest acceptance among the participants.
Direction
PEREZ RIOS, MONICA (Tutorships)
REY BRANDARIZ, JULIA (Co-tutorships)
PEREZ RIOS, MONICA (Tutorships)
REY BRANDARIZ, JULIA (Co-tutorships)
Court
MONTES MARTINEZ, AGUSTIN (Chairman)
RODRÍGUEZ FERNÁNDEZ, Mª DE LA ALMUDENA (Secretary)
VARELA LEMA, MARIA LEONOR (Member)
MONTES MARTINEZ, AGUSTIN (Chairman)
RODRÍGUEZ FERNÁNDEZ, Mª DE LA ALMUDENA (Secretary)
VARELA LEMA, MARIA LEONOR (Member)
Interstitial Cells of Cajal and Enteric Nervous System in Gastrointestinal and Neurological Pathology, Relation to Oxidative Stress
Authorship
L.L.P.
Master in Genetic, Nutritional and Environmental Determinants concerning Growth and Development-NUTRENVIGEN G+D Factors
L.L.P.
Master in Genetic, Nutritional and Environmental Determinants concerning Growth and Development-NUTRENVIGEN G+D Factors
Defense date
02.14.2025 11:45
02.14.2025 11:45
Summary
One of the attacks on cell structures is oxidative stress. In the enteric nervous system (ENS) it is interesting to study the relationship between oxidative processes, gastrointestinal pathology and intestinal nerve plexuses. Through bibliographic review, we analyze the relationship between oxidative stress, ENS and interstitial cells of Cajal (ICC), in gastrointestinal, neurodegenerative and neurodevelopmental pathologies. And, later, we value the bidirectional relationship between the central nervous system and the ENS. Conducting a bibliographic review in PubMed, with the filters: Review, Full Text, 10 years, Humans, with subsequent extension to: Case Reports, Clinical Trial and Meta-Analysis, and older than 10 years. Search algorithms: Enteric nervous system OR ICCs AND oxidative stress; ICC OR ENS AND brain; Parkinson AND ENS NOT microbiota; Alzheimer AND ENS”NOT microbiota; ELA AND ENS NOT microbiota. The MeSH terms for each algorithm: Parkinson; ENS; GIST, Chagas; Postoperative paralytic ileus; Nitric oxide; Plasticity, Oxidative stress, among others. The results are structured in the following sections: 1) ICC in the intestine. 2) Oxidative stress in ICC and ENS. 3) Gastrointestinal disorders related to ICC and ENS. 4) Neurodegenerative diseases affecting the ENS. 5) Neurodevelopmental disorders with involvement of the ENS. ICCs are located in the intestine and participate in enteric neurotransmission. They are the pacemaker cells of the ENS, responsible for the genesis of slow waves. In the main gastrointestinal pathologies, an alteration of the myenteric plexus and its connections with ICC are evident.
One of the attacks on cell structures is oxidative stress. In the enteric nervous system (ENS) it is interesting to study the relationship between oxidative processes, gastrointestinal pathology and intestinal nerve plexuses. Through bibliographic review, we analyze the relationship between oxidative stress, ENS and interstitial cells of Cajal (ICC), in gastrointestinal, neurodegenerative and neurodevelopmental pathologies. And, later, we value the bidirectional relationship between the central nervous system and the ENS. Conducting a bibliographic review in PubMed, with the filters: Review, Full Text, 10 years, Humans, with subsequent extension to: Case Reports, Clinical Trial and Meta-Analysis, and older than 10 years. Search algorithms: Enteric nervous system OR ICCs AND oxidative stress; ICC OR ENS AND brain; Parkinson AND ENS NOT microbiota; Alzheimer AND ENS”NOT microbiota; ELA AND ENS NOT microbiota. The MeSH terms for each algorithm: Parkinson; ENS; GIST, Chagas; Postoperative paralytic ileus; Nitric oxide; Plasticity, Oxidative stress, among others. The results are structured in the following sections: 1) ICC in the intestine. 2) Oxidative stress in ICC and ENS. 3) Gastrointestinal disorders related to ICC and ENS. 4) Neurodegenerative diseases affecting the ENS. 5) Neurodevelopmental disorders with involvement of the ENS. ICCs are located in the intestine and participate in enteric neurotransmission. They are the pacemaker cells of the ENS, responsible for the genesis of slow waves. In the main gastrointestinal pathologies, an alteration of the myenteric plexus and its connections with ICC are evident.
Direction
Leis Trabazo, María Rosaura (Tutorships)
Muñoz Hoyos, Antonio (Co-tutorships)
Agil Abdalla, Ahmad (Co-tutorships)
Leis Trabazo, María Rosaura (Tutorships)
Muñoz Hoyos, Antonio (Co-tutorships)
Agil Abdalla, Ahmad (Co-tutorships)
Court
Leis Trabazo, María Rosaura (Coordinator)
COUCE PICO, MARIA DE LA LUZ (Chairman)
MARTINON TORRES, FEDERICO (Secretary)
Concheiro Guisán, Ana (Member)
Leis Trabazo, María Rosaura (Coordinator)
COUCE PICO, MARIA DE LA LUZ (Chairman)
MARTINON TORRES, FEDERICO (Secretary)
Concheiro Guisán, Ana (Member)