ECTS credits ECTS credits: 4.5
ECTS Hours Rules/Memories Student's work ECTS: 74.2 Hours of tutorials: 2.25 Expository Class: 18 Interactive Classroom: 18 Total: 112.45
Use languages Spanish, Galician
Type: Ordinary Degree Subject RD 1393/2007 - 822/2021
Center Faculty of Biology
Call: First Semester
Teaching: Sin Docencia (En Extinción)
Enrolment: No Matriculable (Sólo Planes en Extinción)
The course attempts to integrate the student other materials to thereby be able to analyze the information flow, and molecular genetics and regulatory systems that operate in cells.
- Subject without teaching (plan extinct)
EXPOSITORY CLASSES (Program of Lectures, 26 hours face-to-face)
I. GENOME STRUCTURE (7h)
Lesson 1. Molecular biology and its origins. The nucleic acids DNA and RNAs (1.5h)
Lesson 2. Condensation of DNA, chromatin and chromosomes (3.5 h)
Lesson 3. Genes and genomes (2h)
II. EXPRESSION OF GENOME AND REGULATION (19h)
(A) CELL SIGNALING AND GENE EXPRESSION (11h)
Lesson 4. General mechanisms of signal transduction by external and internal signals (1.5h)
Lesson 5. Proteins in cell signaling: Transducing proteins, protein interactions and gene regulatory proteins (2.5h)
Lesson 6. Intracellular signaling pathways activated by hydrophilic signals (5h)
Lesson 7. Intracellular signaling pathways activated by hydrophobic signals (2h)
(B) THE REGULATION OF GENE EXPRESSION OF EUKARYOTE GENOME (8h)
Lesson 8. Regulatory RNAs and gene expression regulation (2h)
Lesson 9. The epigenome: Role of chromatin structure in gene control (2h)
Lesson 10. Regulation of gene expression I: Transcriptional regulation (2.5h)
Lesson 11. Regulation of gene expression II: Transport, localization and stability of mRNA and translational control
(3.5h)
INTERACTIVE LESSONS (Seminars program, 10 hours face-to-face)
Seminars on "Research methods and techniques in genes and proteins" (6h, 3 sessions of 2h).
Seminars for the resolution of questionnaires corresponding to the contents of the expository classes (4h, 2 sessions of 2h).
TUTORIALS (5H)
Tutorial 1: at the beginning of the course, it will be used for the detailed presentation of the subject and the teaching guide. 1 hour face-to-face.
Tutorial 2: carrying out the exam corresponding to the seminars. 1 hour face-to-face.
Remaining tutorials: consultation/resolution of doubts and review of basic and general concepts of the subject explained in the expository and interactive classes. At the request of the students. Face-to-face or through MS-Teams, 1 hour long each.
FINAL EXAM (2.5 face-to-face hours)
Completion of a mandatory written test for the evaluation of knowledge and skills.
BASIC BIBLIOGRAFY
- Alberts, B. et al., 2015. Molecular Biology of the Cell. 6th ed. New York: Garland Science.
- Hérraez, A., 2012. Texto ilustrado e interactivo de Biología Molecular e Ingeniería Genética. Conceptos, técnicas y
aplicaciones en ciencias de la salud. 2ª ed. Barcelona: Elsevier.
- Nelson, D.L. & Cox, M.M., 2021. Lehninger. Principles of Biochemistry. 8ª ed. New York: Macmillan International.
- Lodish, H., Berk, A., Kaiser, C.A., Krieger, M., Brestscher, A., Ploegh, H., Martin, K.C., Yaffe, M.B., Amon, A. 2021.
Molecular Cell Biology. 9th ed. New York: Macmillan International.
- Watson, J.D. et al., 2016. Biología molecular del gen. 7ª ed. Buenos Aires: Ed. Médica Panamericana
COMPLEMENTARY BIBLIOGRAFY
- Brown, T.A., 2018. Genomes 4. 4th ed. New York: Garland Science.
- Cantley, L.C., Hunter, T., Sever, R. and Torner, J., 2014. Signal Transduction. Principles, Pathways and Processes.
4th ed. New York: Cold Spring Harbor Laboratory Press.
- Clark, D.P. and Pazdernik, N.J., 2019. Molecular Biology. 2nd ed. Boston: Academic Press.
- Craig, N.L. et al., 2014. Molecular Biology. Principles of Genome Function. 2nd ed. Oxford: Oxford University Press.
- Kraus. G., 2014. Biochemistry of Signal Transduction and Regulation. 5th ed. Weinheim: Wiley-VCH.
- Subject without teaching (plan extinct)
General and basic skills
The competences that appear as general and basics in Memory of Biology Degree
Transversal skills
• CT1. Capacity for analysis and synthesis
• CT2. Capacity for reasoning and argumentation
• CT5. Ability to prepare and present an organized and understandable text
• CT9. Ability to use bibliography and the Internet.
• CT10. Use of information in a foreign language.
• CT11. Ability to solve problems through the integrated application of their knowledge.
Specific skills
• CE1.c. Instrumental knowledge, skills and abilities. Basic techniques in biology.
• CE2.a. Origin and molecular bases of life: concepts, mechanisms and hypotheses.
• CE2.c. Origin and molecular bases of life: molecular biology of the cell.
• CE2.e. Origin and molecular bases of life: analysis of biomolecules and metabolic processes.
• CE2.f. Origin and molecular bases of life: molecular, cellular and tissue analysis.
• CE6.c. Human biology, heredity and evolution: the hereditary material.
• CE6.e -Human biology, heredity and evolution: genetic and evolutionary analysis.
• CE6. F. Human biology, heredity and evolution: the flow of genetic information.
• CE7.a -Biotechnology and biomedicine: biological bases of diseases.
• CE7.g. Biotechnology and biomedicine: clinical and molecular analysis methods.
• Subject without teaching (plan extinct)
- Expository classes: Non-mandatory face-to-face activity. Master classes for the presentation of the lessons of the theoretical program of the subject with the use of waxing and, where appropriate, supported by computer presentations.
The contents, order and time dedicated to each of the topics may be modified, with respect to the program presented in the teaching guide, by the incorporation of new concepts and more recent updates.
- Interactive classes. Seminars on "Research methods and techniques in genes and proteins" will be given by the professor in master class format and they will deal with research techniques in Molecular Biology. They are face-to-face, non-compulsory and assessable.
The seminars for the resolution of questionnaires corresponding to the contents of the expository classes are attended on a voluntary basis. These seminars will consist of problem-based learning, where the students, and the teacher where appropriate, will solve questionnaires related to the topics presented in the lectures. They will allow to reinforce and review concepts explained in theory or doubts of the students. The questionnaires could also be available to students in advance of the seminars themselves, through the virtual classroom.
- Tutorial classes. They will not be compulsory or evaluable, with the exception of the tutoring dedicated to the seminar exam, which does involve an evaluable activity, although not compulsory.
• The final exam is a mandatory face-to-face test for the evaluation of knowledge and skills using a written test in which multiple choice questions, problems similar to those of the seminars and development questions will be formulated, covering the topics covered in the expository classes. and in the corresponding seminars.
It is expressly forbidden for students to distribute, among people outside the course, the teaching material (both written and audiovisual) available on the Virtual Campus or provided by the teaching staff through other channels.
- Subject without teaching (plan extinct)
The learning assessment will be done in person and will consist of:
(a) Evaluation of content (lectures) (Final Exam). Compulsory evaluable activity complementary to continuous evaluation.
The contents of the theoretical program will be evaluated by written face-to-face exam (final exam). The maximum grade obtained in the exam (10 points) is equivalent to 85% of the final grade and as long as a minimum of 80% has been answered of exam questions and achieved a 4.5 out of 10 in his rating.
(b) Evaluation of interactive classes (Continuous assessment). Non-mandatory evaluable activity.
The seminars on "Research methods and techniques in genes and proteins" will be evaluated through a non-mandatory face-to-face written exam that will be graded from 0 to 10 points and the grade obtained will account for 15% of the final grade for the subject. This exam will be carried out in one hour of tutoring after the completion of the corresponding seminars on a date duly informed by the teaching staff. For those students who cannot do it on that date, they can do it together with the expository exam. The exam will consist of questions that could combine test-type questions, relationship of concepts, theoretical questions and reasoning.
(c) Final evaluation. The final grade will be obtained as the weighted average of the partial grades obtained in (a) and (b), which represents, respectively, 85% and 15% of the final grade and as long as it has been achieved in the grade of (a) a minimum of 4.5 points and the minimum response requirement. The lack of qualification in (b) will imply that the student renounces that part of the grade, so that he could obtain, at most, 8.5 points in the final qualification, in the event that in the content exam of the expository classes would have reached 10 points.
• In the second call, the evaluation dependent on the theory exam will be repeated exclusively. In the case of not having taken it previously, the exam corresponding to the seminars will also be carried out, which will be voluntary, as indicated above. In any case, the students will only be evaluated from the seminars once per course.
• In the event of having to repeat the subject in the following academic year (2023-24 or later, where there will only be the right to take an exam), only the note from the seminar exam will be kept if desired, although this exam may be taken again (voluntary) along with the expository classes, which will be compulsory.
• Students repeating the 2021-22 and preceding academic years must carry out the same type of activities/assessment as first-time students since no grade from any preceding academic year is retained.
Plagiarism and improper use of technologies in the performance of tasks or tests: in cases of fraudulent performance of exercises or tests, the provisions of the Regulations for evaluating the academic performance of students and reviewing grades will apply.
EVALUATION OF COMPETENCE
Through the exam of expository classes the following competences will be evaluated:
Transversal skills
CT1, CT2, CT5, CT9, CT10 and CT11
Specific skills
CE1.c, CE2.a, CE2.c, CE2.e, CE2. f, CE6. c, CE6.e, CE6.f, CE7.a and CE7.g
Through the seminar exam, the following skills will be evaluated:
Transversal skills
CT1, CT2, CT9, CT10 and CT11
Specific skills
CE1.c, CE2.a, CE2.e, CE2.f, CE6.e and CE7.g
- Subject without teaching (plan extinct)
• Attendance at all teaching activities.
• Participation in the corresponding classes, answering orally to the questions/questions posed by the teacher, both in the class itself and in those presented in the different lessons of the theoretical program and those specific to the seminars, although they do not count towards the evaluation.
• Make summaries / diagrams or scripts that synthesize the important contents of each of the lessons of the program, trying to combine and relate different aspects that are explained in each one of them.
• Self-evaluation of the content understanding. The student should try to generate, by himself and using books, especially those recommended in the bibliography, a catalog of questions and answers so that he can face the exam with more possibilities of success.
• Make use of tutorials for any type of matter related to the subject.
It is recommended that for a better understanding of the subject of Molecular Biology previous knowledge of subjects such as Biochemistry I/II, Genetics I/II, Cell Biology, Animal and Plant Physiology, Microbiology, in addition to basic notions of chemistry (organic and inorganic).
The information available to the student will be left through the virtual classroom that will be enabled for this subject and contact/communication with the student will be established (through the institutional email and/or the MS-Teams platform.
Plagiarism and improper use of technologies in the performance of tasks or tests: in cases of fraudulent performance of exercises or tests, the provisions of the Regulations for evaluating the academic performance of students and reviewing grades will apply.
It is expressly forbidden for students to distribute, among people outside the course, the teaching material (both written and audiovisual) available on the Virtual Campus or provided by the teaching staff through other channels.
Primitivo Barja Francisco
- Department
- Biochemistry and Molecular Biology
- Area
- Biochemistry and Molecular Biology
- Phone
- 881816931
- primi.barja [at] usc.es
- Category
- Professor: University Lecturer
Maria Lourdes Dominguez Gerpe
- Department
- Biochemistry and Molecular Biology
- Area
- Biochemistry and Molecular Biology
- ml.dominguez.gerpe [at] usc.es
- Category
- Professor: Temporary supply professor to reduce teaching hours
| 01.22.2025 16:00-20:00 | Grupo de examen | Classroom 08. Louis Pasteur |
| 06.13.2025 10:00-14:00 | Grupo de examen | Classroom 01. Charles Darwin |