ECTS credits ECTS credits: 6
ECTS Hours Rules/Memories Hours of tutorials: 1 Expository Class: 32 Interactive Classroom: 24 Total: 57
Use languages Spanish, Galician
Type: Ordinary Degree Subject RD 1393/2007 - 822/2021
Departments: Biochemistry and Molecular Biology
Areas: Biochemistry and Molecular Biology
Center Faculty of Biology
Call: Second Semester
Teaching: With teaching
Enrolment: Enrollable | 1st year (Yes)
- Identify and distinguish the structure, properties and function of biomolecules.
- Identify the relationship between the structure and function of biomolecules.
- Apply the principles of thermodynamics to biological systems.
- Distinguish the different classes of enzymes and their catalysis mechanisms, as well as the principles of enzyme regulation.
- Know the different components of biological membranes and their functionality.
- Know how to carry out purification processes and analysis of biomolecules.
- Know how to measure enzyme activities.
EXHIBITION CLASSES (30 hours)
INTRODUCTION
• Unit 1. Biochemical science. Molecular design of life (2 h).
BIOLOGICAL STRUCTURE AND FUNCTION OF BIOMOLECULES
• Unit 2. Carbohydrates (2 h).
• Unit 3. Lipids (2 h).
• Unit 4. Nucleotides and nucleic acids (2 h).
• Unit 5. Amino acids, peptide bond and peptides (2 h).
• Unit 6. Three-dimensional structure and functionality of proteins (3 h).
• Unit 7. Function of proteins. Myoglobin and hemoglobin (3 h).
ENZYMOLOGY
• Unit 8. Enzymes: structure and function (3 h).
• Unit 9. Kinetics of the enzymatic reaction and inhibition (3 h).
• Unit 10. Regulation of the enzymatic reaction (3 h).
INTRODUCTION TO METABOLISM AND ITS REGULATION
• Unit 11. Bioenergetics: energy exchanges and high energy level compounds (2 h).
• Unit 12. Biological membranes and transport mediated in metabolism (2 h).
• Unit 13. Introduction to metabolism and its regulation (1 h).
PROGRAM OF INTERACTIVE CLASSES / PRACTICAL CLASSES (14 h)
• PRACTICE 1. Obtaining extract of animal tissue (calf liver) and fractionation of cellular organelles. Preparation of reagents (2 h).
• PRACTICE 2. Obtaining and analysis of DNA from eukaryotic cell nuclei. Electrophoretic analysis in agarose gels (3 h).
• PRACTICE 3. Quantitative determination of proteins. Lowry's method (3 h).
• PRACTICE 4. Carbohydrate identification (3 h).
• PRACTICE 5. Enzymology: kinetics and enzyme inhibition. (3 h)
PROGRAM OF INTERACTIVE CLASSES / SEMINARS (10 h)
• Seminar 1: carbohydrates and lipids. (2 h)
• Seminar 2: amino acids and proteins. (2 h)
• Seminar 3: enzymology I, enzymatic activity. (2 h)
• Seminar 4: enzymology II, enzyme inhibition. (2 h)
• Seminar 5: biological membranes and bioenergetics. (2 h)
TUTORIALS (1 h).
It is located at the beginning of the course to explain the development of the subject and the evaluation table. The MS-Teams platform will be used.
EXAM (2 h) In-person activity
Compulsory face-to-face written exam of the contents of expository and seminars.
Basic
• Berg, J.M., Tymoczko, J.L. & Stryer L., 2015. Bioquímica con aplicaciones clínicas. 7ª ed. Barcelona: Reverté.
• Mathews, C.K., Van Holde, K.E. & Anthony-Cahill, S.J., 2013. Bioquímica. 4ª ed. Madrid: Pearson.
• Rodwell, V.W., Bender, D.A., Botham, K.M., Kennelly, P.J. & Weil, P.A., 2018. Harper Bioquímica ilustrada. [on line] 31ª ed. México: McGraw-Hill/Interamericana. Available in: https://accessmedicina-mhmedical-com.ezbusc.usc.gal/Book.aspx?bookid=27…
• Nelson, D.L. & Cox, M.M., 2021. Lehninger Principles of Biochemistry. 8th ed. New York: Macmillan International Higher Education.
• Voet, D., Voet, J. & Pratt, C., 2016. Fundamentos de bioquímica: la vida a nivel molecular. 4ª ed. Buenos Aires: Ed. Médica Panamericana.
• McKee, T. & McKee, J.R., 2014. Bioquímica. Las bases moleculares de la vida. [on line] 5ª ed. México: McGraw-Hill/Interamericana. Available in: https://accessmedicina-mhmedicalcom.ezbusc.usc.gal/Book.aspx?bookid=1960
Complementary
- Roca, P., Oliver, J. & Rodríguez, A.M., 2003. Bioquímica. Técnicas y Métodos. Madrid: Hélice.
- Alberts, B., et al., 2016. Biología molecular de la célula. 6ª ed. Barcelona: Omega
- Lodish, H., et al., 2016. Biología celular y molecular. 7ª ed. Buenos Aires: Editorial Médica Panamericana.
- Paniagua, R. et al., 2017. Biología celular y molecular. [on line] 4ª ed. Madrid: McGraw-Hill Interamericana. Available in: https://accessmedicina-mhmedical-com.ezbusc.usc.gal/Book.aspx?bookid=22…
Other resources
- http://biomodel.uah.es. Website of University of Alcalá de Henares
- http://www.ncbi.nlm.nih.gov/guide/ (The National Center for Biotechnology Information, (NCBI) main source of databases (nucleotides, genes and genomes, and bioinformatics tools.
- BUSC electronic resources: Cell, Nature, Science, Sciencedirect, etc.
- http://www.sebbm.es/BioROM/indices/index.html (website of the Spanish Society of Biochemistry and Molecular Biology, and its teaching resources).
Knowledge/content
Con01; Con02; Con03; Con05; Con06; Con09
Abilities/skills
H/D01; H/D02; H/D03; H/D07; H/D08; H/D09; H/D10; H/D14
Competencies
Com01; Comp02; Comp03; Comp04; Comp05; Comp06
The subject is designed to improve the Active Learning of the students. The expository classes are conceived as general introductions to each topic, which will be complemented by the rest of the proposed activities. These activities are individual study, carrying out practical activities in the laboratory and a practice notebook, solving questions in seminars (ABP) and solving doubts about the subject in tutorials.
Attendance at all activities is MANDATORY in accordance with the subject file in the Degree Report, except for students with official dispensation, but only those specified in the following section will be REQUIRED to pass the subject.
The individual study will be carried out with organized and detailed information provided by the teachers. The basis of this information will be the recommended basic bibliography, which will be complemented with additional information.
In the expository classes, the teaching staff will explain the concepts of the subject with the support of audiovisual and computer media. It can have different formats (theory, problems and/or general examples, general guidelines for the subject), promoting the participation of the students.
There will be 5 seminars of 2 hours each with the objective of carrying out, in small working groups, practical questions (problems, reasoning questions or PBL, etc.) related to the subjects of the subject, which will serve to deepen their knowledge. In these seminars the students will be able to take notes, books and all the necessary teaching material.
Attendance and completion of the seminars will be voluntary. During the seminar, the students will be able to actively participate in the resolution of the proposed problems and questions, which will be evaluated. At the end of each seminar, individual evaluable questionnaires will be carried out in electronic format by connection to the Virtual Campus, and its content is subject of examination.
The laboratory practices are practical classes in which the theoretical contents are applied, through the observation and handling of biological material, instruments, etc., following the protocols prepared for this purpose. Teachers can count on the support of audiovisual and computer media. The laboratory practices are organized in 5 mandatory sessions (except for repeaters) of 2 to 3 hours. The students must carry out a series of experimental tests, collect the results obtained, review the content presented by the teachers and analyze everything properly to answer the questions and exercises formulated in the practice notebook, to prepare a test report. individual and evaluable practices. Attendance at practices and delivery of the practice report are MANDATORY AND REQUIREMENTS to pass the course.
All the expositive and interactive classes (except for tutoring) will be face-to-face and will take place in the classroom following the official calendar and the subject calendar.
Doubt tutorials, at the request of the students, can be in person or by electronic mechanisms in agreement with the students (Virtual Campus, email or MS-Teams).
It is expressly prohibited for students to distribute the teaching material (both written and audiovisual) available on the Virtual Campus to people outside the course.
Plagiarism and misuse of technologies in carrying out tasks or tests:
In the case of fraudulent performance of exercises or tests, the provisions of the Regulations for the evaluation of the academic performance of students and the review of grades will be applied.
1. General criteria: Not evaluable compulsory activities, Evaluable compulsory activities and Evaluable non-compulsory activities.
Attendance at all activities is MANDATORY in accordance with the subject file in the Degree Report except for students with official dispensation, although not all of them will be a mandatory requirement. The FINAL TEST (exam), ATTENDANCE TO LABORATORY PRACTICES and the delivery of CONTINUOUS EVALUATION 1 (Practice report / Laboratory data and preparation of answers) will be a MANDATORY REQUIREMENT to pass the subject.
CONTINUOUS ASSESSMENT will only be carried out once per course and will be valid for both assessment opportunities. Therefore, in the second evaluation opportunity, only the FINAL TEST will be repeated, maintaining the qualification obtained in the continuous evaluation. The weighting of each part of the evaluation will be the same on both occasions. To pass the course, the sum of the exam and continuous assessment must be at least 5/10 points in total, in addition to meeting the specific requirements indicated below.
There will be no compensatory mechanisms for non-attendance and/or performance of any compulsory and/or evaluable activity. No partial exams will be carried out.
2. Specific evaluation criteria and presentation criteria.
Instrument: FINAL EXAM
Completion / Criteria: the final written PRESENTIAL exam is a MANDATORY REQUIREMENT (65% of the final grade) that is considered as a mandatory complementary test to the continuous assessment for all students. The subject evaluated in the exam includes the contents of the lectures and seminars. The exam will have test part (30% of the mark) and a section of development questions and problems (70% of the mark) that will cover all aspects related to the content of the subject (except the practices). To pass it, you must qualify on all the questions of the exam development.
In the final exam, a minimum mark of 4/10 points must be achieved, otherwise, the continuous evaluation will not be added, so that the final grade of the subject will be exclusively the weighted exam.
Weight: up to 65% of the total grade.
Assessed skills: Con01, 02, 03, 05, 06, 09; H/D01, 03, 07, 08; Com01, 02, 05, 06.
Instrument: CONTINUOUS ASSESSMENT 1
Completion / Criteria: delivery of the practical report / Laboratory data and preparation of the answers. Delivery of MANDATORY REQUIREMENT through the Virtual Campus or institutional email.
Weight: up to 15% of the final grade.
It will only be added to the final grade if the minimums specified for the exam have been achieved.
Assessed skills: Con01, 02, 05, 09; H/D02, 08, 09, 10; Com 01, 02, 03, 04, 05, 06.
Instrument: CONTINUOUS ASSESSMENT 2
Completion/Criteria: Active participation in seminar classes. Activities: resolution in the classroom of problems and questions proposed by classmates or teachers. Its completion IS NOT A MANDATORY REQUIREMENT.
Weight: up to 5% of the final grade.
It will only be added to the final grade if the minimums specified for the exam have been achieved.
Assessed skills: Con01, 02, 05, 06, 09; H/D01, 03, 07, 08, 10; Com01, 02, 03, 05, 06.
Instrument: CONTINUOUS ASSESSMENT 3
Completion / Criteria: previous autonomous work to studying the contents and face-to-face during the seminars. Activities: completion of the questionnaires in the Virtual Campus at the end of the seminars. Its completion IS NOT A MANDATORY REQUIREMENT.
Weight: up to 15% of the final grade.
It will only be added to the final grade if the minimums specified for the exam have been achieved.
Assessed skills: Con01, 02, 05, 06, 09; H/D03, 07, 08; Com01, 02, 03.
3. Evaluation of repeaters.
As an exception for repeaters, they may keep the mark for CONTINUOUS ASSESSMENT 1 if they have obtained at least a 5 out of 10 in one of the two previous courses and have met the requirements for attendance at laboratory practices. If this minimum grade is not reached, the repeaters must do the laboratory practices again and present the practice report.
CONTINUOUS ASSESSMENT 2 and 3, as its completion is not a mandatory requirement, may be retained from two previous courses regardless of your grade.
All repeating students must take the FINAL EXAM. The weight of each evaluation instrument will be the same as that indicated above.
TRAINING ACTIVITY
Attendance hours: 57 hours
Expository Classes: 30 hours; 100% attendance
Interactive classes-Seminars: 10 hours; 100% attendance
Interactive classes-Laboratory: 14 hours; 100% attendance
Interactive classes-Tutorials: 1 hour; 100% attendance
Exam: 2 hours; 100% attendance
Non-attendance hours 93 hours
Dedicated to individual study for the preparation of the subject and seminars for the preparation of practice reports during the course, and to prepare for the exam.
Total workload: 57 hours of face-to-face classes and 93 hours of personal work = 150 total hours (25 hours / ECTS x 6 ECTS = 150h).
- Attendance and active participation in class. Although attendance and completion of the seminars are not mandatory requirements, it is strongly recommended since: i) a large part of the expository material is reviewed; ii) is also subject to review; iii) a questionnaire is evaluated and a significant percentage of the final grade is obtained); iv) the type of questions addressed are very similar to some that will appear on the exam. It is also important to carry out the problems and questions that do not have time to ask in each seminar session and that will be available to the students.
- For each class hour, two hours of study, using bibliographic material to understand and deepen the information obtained in class (it is essential that study time be as close as possible to the time of class).
- Weekly study and review of the subject taught and/or preparation of the proposed seminars before their presentation in class.
- Clarification with the teachers of possible doubts.
- Review of the final exam.
- Interest and attention in the new advances in this discipline that are spread through the media.
If they do not have previous knowledge of Biology and Chemistry from high school, students must obtain it as soon as possible during the course.
Contributions for continuous evaluation (with the exception of CONTINUOUS EVALUATION 2) will be made by telematic means: Virtual Campus or institutional email.
The non-face-to-face direct communication channels with the students, in addition to the subject's operational Virtual Campus available to students, and email, will be tutorials, forums or virtual sessions through MS-Teams.
It is expressly prohibited for students to distribute the teaching material (both written and audiovisual) available on the Virtual Campus to people outside the course.
Plagiarism and misuse of technologies in carrying out tasks or tests:
In the case of fraudulent performance of exercises or tests, the provisions of the Regulations for the evaluation of the academic performance of students and the review of grades will be applied.
Cristina Diaz Jullien
- Department
- Biochemistry and Molecular Biology
- Area
- Biochemistry and Molecular Biology
- Phone
- 881816932
- cristina.diaz [at] usc.es
- Category
- Professor: Temporary PhD professor
Guillermo Covelo Artos
Coordinador/a- Department
- Biochemistry and Molecular Biology
- Area
- Biochemistry and Molecular Biology
- Phone
- 881816930
- guillermo.covelo [at] usc.es
- Category
- Professor: Temporary PhD professor
Oscar Javier Cordero Santamaria
- Department
- Biochemistry and Molecular Biology
- Area
- Biochemistry and Molecular Biology
- Phone
- 881816935
- oscarj.cordero [at] usc.es
- Category
- Professor: University Professor
Ma Del Pilar Arias Crespo
- Department
- Biochemistry and Molecular Biology
- Area
- Biochemistry and Molecular Biology
- Phone
- 881816933
- pilar.arias [at] usc.es
- Category
- Professor: University Lecturer
| Tuesday | |||
|---|---|---|---|
| 10:00-11:00 | Grupo /TI-ECTS01 | Spanish | Virtual classroom |
| 11:00-12:00 | Grupo /TI-ECTS02 | Spanish | Virtual classroom |
| 12:00-13:00 | Grupo /TI-ECTS03 | Spanish | Virtual classroom |
| 13:00-14:00 | Grupo /TI-ECTS04 | Spanish | Virtual classroom |
| 16:00-17:00 | Grupo /CLE_02 | Spanish | Classroom 04: James Watson and Francis Crick |
| 17:00-18:00 | Grupo /CLE_01 | Spanish | Classroom 03. Carl Linnaeus |
| Wednesday | |||
| 10:00-11:00 | Grupo /TI-ECTS05 | Spanish | Virtual classroom |
| 11:00-12:00 | Grupo /TI-ECTS06 | Spanish | Virtual classroom |
| 12:00-13:00 | Grupo /TI-ECTS07 | Spanish | Virtual classroom |
| 13:00-14:00 | Grupo /TI-ECTS08 | Spanish | Virtual classroom |
| 16:00-17:00 | Grupo /CLE_02 | Spanish | Classroom 04: James Watson and Francis Crick |
| 17:00-18:00 | Grupo /CLE_01 | Spanish | Classroom 03. Carl Linnaeus |
| Thursday | |||
| 10:00-11:00 | Grupo /TI-ECTS09 | Spanish | Virtual classroom |
| 11:00-12:00 | Grupo /TI-ECTS10 | Spanish | Virtual classroom |
| 12:00-13:00 | Grupo /TI-ECTS11 | Spanish | Virtual classroom |
| 13:00-14:00 | Grupo /TI-ECTS12 | Spanish | Virtual classroom |
| Friday | |||
| 11:00-12:00 | Grupo /TI-ECTS13 | Spanish | Virtual classroom |
| 12:00-13:00 | Grupo /TI-ECTS14 | Spanish | Virtual classroom |
| 06.03.2025 16:00-20:00 | Grupo /CLE_01 | Classroom 01. Charles Darwin |
| 06.03.2025 16:00-20:00 | Grupo /CLE_01 | Classroom 02. Gregor Mendel |
| 06.03.2025 16:00-20:00 | Grupo /CLE_01 | Classroom 03. Carl Linnaeus |
| 07.04.2025 16:00-20:00 | Grupo /CLE_01 | Classroom 01. Charles Darwin |
| 07.04.2025 16:00-20:00 | Grupo /CLE_01 | Classroom 02. Gregor Mendel |