ECTS credits ECTS credits: 6
ECTS Hours Rules/Memories Hours of tutorials: 3 Expository Class: 27 Interactive Classroom: 21 Total: 51
Use languages Spanish, Galician
Type: Ordinary Degree Subject RD 1393/2007 - 822/2021
Departments: Biochemistry and Molecular Biology
Areas: Biochemistry and Molecular Biology
Center Faculty of Biology
Call: First Semester
Teaching: With teaching
Enrolment: Enrollable
To
- Learn to identify and distinguish the structure, properties and function of biomolecules.
- Learn to carry out processes of purification and analysis of biomolecules.
- Identify the relationship between the structure and function of biomolecules.
- Distinguish the different classes of enzymes and their catalysis mechanisms, as well as the principles of enzymatic regulation.
- Learn to measure enzymatic activities.
- Apply the principles of thermodynamics to biological systems.
- List the mechanisms and elements of cell signalling.
MAGISTER CLASSES (28 hours face-to-face)
• Lesson 1. Biochemical science. Molecular design of life (2h).
• Lesson 2. Carbohydrates. General characteristics and biological function (2h).
• Lesson 3. Lipids. General characteristics and biological function (2h).
• Lesson 4. Nucleotides and nucleic acids (2h).
• Lesson 5. Amino acids, peptide bond and peptides (2h).
• Lesson 6. Three-dimensional structure and functionality of proteins. Myoglobin and hemoglobin (2h).
• Lesson 7. Enzymes: structure and function (2h).
• Lesson 8. Kinetics of the enzymatic reaction. Inhibitions (3h).
• Lesson 9. Regulation of the enzymatic reaction (2h).
• Lesson 10. Bioenergetics: study of energy transformations and exchanges (2h).
• Lesson 11. Biological membranes. Structure and properties. Mechanisms of transport through the membrane (2h).
• Lesson 12. Cell signaling and its mechanisms (2h).
• Lesson 13. Introduction to metabolism and its regulation (1h).
INTERACTIVE CLASSES / SEMINARS PROGRAM (7 hours face-to-face)
Resolution, in small work groups or individually, to be carried out in the classroom, of practical questions (problems, reasoning questions, etc.) related to the topics of the expository material, which serve to deepen their knowledge, with the following topics:
• Seminar 1: carbohydrates (1h)
• Seminar 2: lipids (1h)
• Seminar 3: amino acids (1h)
• Seminar 4: proteins (1h)
• Seminar 5: biological membranes and bioenergetics (1h)
• Seminar 6: enzymatic activity (1h)
• Seminar 7: enzyme inhibition (1h)
LABORATORY PROGRAM (PRESENTIAL) (15 hours face-to-face)
To be carried out in the laboratory.
• PRACTICE 1. Obtaining extracts from animal tissue (calf liver) and fractionation of cellular organelles. Preparation of reagents (3 h).
• PRACTICE 2. Obtaining and analysis of DNA from eukaryotic cell nuclei. Electrophoretic analysis on agarose gels (3 h).
• PRACTICE 3. Quantitative determination of proteins. Lowry's method (3 h).
• PRACTICE 4. Identification of glycids (3 h).
• PRACTICE 5. Enzymology: kinetics and enzyme inhibition (3 h).
TUTORING PROGRAM (1 hour online)
It is placed at the beginning of the course to explain the development of the Course and the Assessment System. Another two would be used to answer common doubts on the development of the Course and its contents, on demand.
BASIC
+ Berg, J.M., Tymoczko, J.L. y Stryer L., 2015. Bioquímica con aplicaciones clínicas. 7ª ed. Barcelona: Reverté.
(https://www-ingebook-com.ezbusc.usc.gal/ib/NPcd/IB_BooksVis?cod_primari…)
+ Mathews, C.K., Van Holde, K.E. & Anthony-Cahill, S.J., 2013. Bioquímica. 4ª ed. Madrid: Pearson
(https://www-ingebookcom.ezbusc.usc.gal/ib/NPcd/IB_BooksVis?cod_primaria…)
+ *Rodwell, V.W., Bender, D.A., Botham, K.M., Kennelly, P.J. y Weil, P.A., 2024. Harper Bioquímica ilustrada. [en línea] 32ª ed. México: McGraw-Hill/Interamericana. (https://accessmedicina-mhmedicalcom.
ezbusc.usc.gal/book.aspx?bookid=3284)
+ Nelson, D.L. y Cox, M.M., 2018. Lehninger Principios de Bioquímica. 7ª ed. Barcelona: Omega.
+ Voet, D., Voet, J.G.y Pratt, C.W., 2016. Fundamentos de bioquímica: la vida a nivel molecular. 4ª ed. Buenos Aires: Ed. Médica Panamericana.
(https://mieureka-medicapanamericana-com.ezbusc.usc.gal/viewer/fundament…)
+ *McKee, T., y McKee, J.R., 2014. Bioquímica. Las bases moleculares de la vida.[en línea] 5ª ed. México: McGraw-Hill/Interamericana. Disponible en: https://accessmedicina-mhmedical-com.ezbusc.usc.gal/Book.aspx?bookid=29… (online edition 2020).
COMPLEMENTARY
• *Sánchez Enríquez, S., Flores Alvarado, L.J., Gurrola Díaz, C.M., Heredia Chávez. P., 2014, Manual de prácticas de laboratorio de bioquímica. [en línea] 3ª ed. México: McGraw-Hill/Interamericana. Disponible en: https://accessmedicina-mhmedical-com.ezbusc.usc.gal/Book.aspx?bookid=14…
• Roca, P., Oliver, J. y Rodríguez, A.M., 2003. Bioquímica. Técnicas y Métodos. Madrid: Hélice.
• Alberts, B., et al., 2016. Biología molecular de la célula. 6ª ed. Barcelona: Omega
• Lodish, H., et al., 2016. Biología celular y molecular. 7ª ed. Buenos Aires: Editorial Médica Panamericana.
ANOTHER RESOURCES
-http://biomodel.uah.es. Sitio web Universidad Alcalá de Henares
-http://www.sebbm.es/BioROM/indices/index.html
-http://www.pubmed.com (books)
-Recursos electrónicos de la BUSC: Cell, Nature, Science, Sciencedirect, etc.
1. Knowledge/content
•Con01: Know the most important concepts, methods and results of the different branches of Biotechnology.
•Con02: Have an integrated vision of the functioning of cells and organisms, including their biomolecules, metabolism, gene expression, relationship between cellular compartments, as well as perception, signaling and communication mechanisms.
2. Abilities/skills
•H/D01: Think in an integrated way and approach problems from different perspectives with critical reasoning.
•H/D02: Search, process, analyze/interpret and synthesize relevant information and results from various sources and obtain conclusions on topics related to Biotechnology.
•H/D03: Organize and plan your work.
•H/D04: Interpret experimental results and identify consistent and inconsistent elements.
•H/D05: Work as a team.
•H/D11: Understand and know how to apply the physicochemical principles of biological processes with application in Biotechnology, as well as the main tools used to investigate them.
•H/D12: Know how to apply instrumental techniques and work protocols in a laboratory, applying regulations and techniques related to safety and hygiene, waste management and quality.
3. Competencies
•Comp01: That students have the ability to gather and interpret relevant data (normally within their area of study) to make judgments that include reflection on relevant topics of a social, scientific or ethical nature.
•Comp02: That students are able, both in writing and orally, to debate and transmit information, ideas, problems and solutions related to Biotechnology to both a specialized and non-specialized/general public.
•Comp03: That students have developed those learning skills necessary to undertake further studies with a high degree of autonomy.
•Comp04: That students know how to apply the theoretical-practical knowledge acquired in the degree in a professional manner and are competent in posing/solving problems, as well as in the elaboration/defense of arguments in both academic and professional contexts related to innovation and the biotechnology industry.
•Comp05: Study and learn autonomously, with organization of time and resources, new knowledge and techniques in Biotechnology and acquire the ability to work as a team.
The course is designed to improve the Active Learning of students. The expository classes are conceived as general introductions to each topic, which will be complemented with the rest of the proposed activities. These activities are the individual study, the realization of practical activities in the laboratory and a practical notebook, the resolution of questions in seminars (PBL) and the resolution of doubts of the matter in tutorials.
Attendance at all activities is MANDATORY according to the Title Memory, except for students with official dispensation, but it will not be a REQUIREMENT to pass the subject, except those indicated below.
The individual study will be carried out with organized and detailed information provided by the teachers. The basis of this information will be the recommended basic bibliography, which will be supplemented with additional information.
In the magister classes, the teacher will explain the concepts of the subject with the support of audio-visual and computer media. It can have different formats (theory, problems and / or general examples, general guidelines for the topic), promoting student participation.
There will be 7 seminars of 1 hour each with the aim of carrying out, in small work groups, practical questions (problems, reasoning questions, PBL, etc.) related to the subjects of the subject, which will serve to deepen your knowledge. In these seminars you can bring notes, books and all the teaching materials you need. Attendance and the conduct of seminars will be voluntary, the response bulletins will be evaluated. At the end of each seminar, individual questionnaires will be held evaluable in electronic format by connection to the virtual campus, and their content will be examined.
Laboratory practices are practical classes in which the theoretical contents are applied, through the observation and management of biological material, instruments, etc., following the protocols prepared for this purpose. The teacher can count on the support of audio-visual and computer media. Laboratory practices are organized in 5 compulsory sessions (except for repeaters) of 2.5 or 3.5 hours. Students must carry out a series of experimental tests, collect the results obtained, review the content presented by the teachers and analyse everything appropriately to answer the questions and exercises formulated in the practice notebook, to prepare an individual practice report for their mandatory contribution. that will be evaluated.
All magister and interactive classes, as well as tutoring, will be face-to-face and will be held in the classroom following the official calendar and the calendar of the subject, provided that its organization is compatible with the adoption of the established measures and the Protocols for protection of the health of the University of Santiago de Compostela.
The tutorial will be online, or, at the request of the students, can be in person or by electronic mechanisms in agreement with the students (Virtual Campus, email or MS-Teams).
It is expressly forbidden for students to distribute the teaching material (both written and audiovisual) available on the Virtual Campus to people outside the course.
Plagiarism and misuse of technologies in completing tasks or tests:
In the event of fraudulent completion of exercises or tests, the provisions of the Regulations for the evaluation of students' academic performance and the review of grades will apply.
1. General criteria: Mandatory non-evaluable activities, Mandatory evaluable activities and Non-mandatory evaluable activities.
Attendance at all activities is MANDATORY according to the subject sheet in the Degree Report, except for students with official dispensation, although not all of them will be a mandatory requirement. The FINAL TEST, ATTENDANCE TO LABORATORY PRACTICES and CONTINUOUS EVALUATION 1 (Practice report / Laboratory data and preparation of answers) will be a MANDATORY REQUIREMENT to pass the subject.
CONTINUOUS EVALUATION will only be carried out once per course and will be used for both evaluation opportunities. Therefore, in the second evaluation opportunity, only the FINAL TEST will be repeated, maintaining the grade obtained in the continuous evaluation. The weighting of each evaluation part will be the same on both occasions. To pass the subject, the sum of the exam and continuous evaluation must be at least 5/10 points in total, in addition to meeting the specific requirements indicated below.
There will be no compensatory mechanisms for non-attendance and/or completion of any mandatory and/or evaluable activity.
2. Specific evaluation criteria and presentation criteria.
Instrument: FINAL TEST
Completion / Criteria: the written IN-PERSON final exam is a MANDATORY REQUIREMENT (65% of the final grade) which is considered as a mandatory complementary test to the continuous evaluation for all students. The subject evaluated in the exam includes the contents of the expository classes and seminars. The exam will have a multiple choice questionary part (30% of the grade) and a section of development questions and problems (70% of the grade) that will cover all aspects related to the content of the subject (except the practices). To pass it, you must qualify on all the development questions of the exam.
In the final exam, a minimum grade of 4/10 points must be achieved, otherwise, the continuous evaluation will not be added, so that the final grade for the subject will be exclusively the weighted one of the exam.
Weighting: up to 65% of the total grade.
Learning outcomes: Con01,02; H/D01,03,04,011; Comp01,02,03
Instrument: CONTINUOUS EVALUATION 1
Completion / Criteria: delivery of the practice report / Laboratory data and preparation of answers. Delivery of MANDATORY REQUIREMENT through the Virtual Campus or institutional email.
Weighting: up to 15% of the final grade.
It will only be added to the final grade if the minimums specified for the exam have been obtained.
Learning outcomes: Con01,02; H/D01,02,03,04,05,011,012; Comp01,02,03,04,05
Instrument: CONTINUOUS EVALUATION 2
Completion/Criteria: Active participation in seminar classes. Activities: resolution in the classroom of problems and questions proposed by classmates or teachers. Its completion IS NOT A MANDATORY REQUIREMENT.
Weighting: up to 5% of the final grade.
It will only be added to the final grade if the minimums specified for the exam have been obtained.
Learning outcomes: Con01,02; H/D01,02,03,04,05,011; Comp01,02,03,04,05
Instrument: CONTINUOUS EVALUATION 3
Completion / Criteria: prior autonomous work studying the contents and in person during the seminars. Activities: completion of the questionnaires on the Virtual Campus at the end of the seminars. Its completion IS NOT A MANDATORY REQUIREMENT.
Weighting: up to 15% of the final grade.
It will only be added to the final grade if the minimums specified for the exam have been obtained.
Learning outcomes: Con01,02; H/D01,04,011; Comp01,02,03,
3. Evaluation of repeaters.
As an exception for repeaters, they may keep their CONTINUOUS EVALUATION 1 grade if they have obtained at least a 5 out of 10 in any of the two previous courses and have met the requirements for attendance at laboratory practices. If this minimum grade is not reached, repeaters must do the laboratory practices again and present the practice report.
CONTINUOUS EVALUATION 2 and 3, since its completion is not a mandatory requirement, may be retained from two previous courses regardless of your grade.
All repeating students must take the FINAL TEST. The weight of each evaluation instrument will be the same as indicated above.
Presential hours: 54 hours
28 hours of exposition
15 practical laboratory hours
7 hours of seminars
1 hours of tutoring
3 hours of exam
Non-presential hours: 96 hours
86 hours of dedication to individual study, 10 hours to the elaboration of the memory of practices.
Total volume of work: 150 total hours (25 hours / ECTS x 6 ECTS = 150h).
- Attendance and active participation in class. Although attending and conducting the seminars are not mandatory, it is strongly recommended since: i) a large part of the exhibition material is reviewed; ii) is also subject to assessment; iii) questionnaires are evaluated (a significant percentage of the final grade); iv) the type of problems and questions addressed are very similar to some that will appear on the exam. It is also important to address problems and questions that you don't have time to ask in each seminar session and that will be available to students.
- For each hour of class two hours of study, using bibliographic material to understand and deepen the information obtained in class (it is essential that study time is as close as possible to class time).
- Study and weekly review of the taught subject and/or preparation of the proposed seminars before their presentation in class.
- Clarification with the teacher of possible doubts.
- Review of the final exam.
- Interest and attention in the new advances of this discipline that spread through the mass media, necessary to deep thinking.
Previous knowledge from the Biology and Chemistry courses in high school is supposed. If it is not the case, the student should learn it on its own.
Contributions to the Continuous Assessment (except CONTINUOUS ASSESSMENT 2) will be made electronically, through the Virtual Campus or the institutional email.
Direct communication channels with students, in addition to the Subject’s operational Virtual Campus and the institutional email available, will be tutorials, forums or virtual sessions through MS Teams.
It is expressly forbidden for students to distribute the teaching material (both written and audiovisual) available on the Virtual Campus to people outside the course.
Plagiarism and misuse of technologies in completing tasks or tests:
In the event of fraudulent completion of exercises or tests, the provisions of the Regulations for the evaluation of students' academic performance and the review of grades will apply.
Cristina Diaz Jullien
- Department
- Biochemistry and Molecular Biology
- Area
- Biochemistry and Molecular Biology
- Phone
- 881816932
- cristina.diaz [at] usc.es
- Category
- Professor: Temporary PhD professor
Guillermo Covelo Artos
- Department
- Biochemistry and Molecular Biology
- Area
- Biochemistry and Molecular Biology
- Phone
- 881816930
- guillermo.covelo [at] usc.es
- Category
- Professor: Temporary PhD professor
Oscar Javier Cordero Santamaria
Coordinador/a- Department
- Biochemistry and Molecular Biology
- Area
- Biochemistry and Molecular Biology
- Phone
- 881816935
- oscarj.cordero [at] usc.es
- Category
- Professor: University Professor
Daniel Abella López
- Department
- Biochemistry and Molecular Biology
- Area
- Biochemistry and Molecular Biology
- daniel.abella [at] rai.usc.es
- Category
- Ministry Pre-doctoral Contract
Adrián López Teijeiro
- Department
- Biochemistry and Molecular Biology
- Area
- Biochemistry and Molecular Biology
- adrianlopez.teijeiro [at] usc.es
- Category
- Ministry Pre-doctoral Contract
Maria Blanquer Garate
- Department
- Biochemistry and Molecular Biology
- Area
- Biochemistry and Molecular Biology
- maria.blanquer.garate [at] usc.es
- Category
- USC Pre-doctoral Contract
| Monday | |||
|---|---|---|---|
| 16:00-17:00 | Grupo /CLE_01 | Spanish | Classroom 08. Louis Pasteur |
| Wednesday | |||
| 16:00-17:00 | Grupo /CLE_01 | Spanish | Classroom 08. Louis Pasteur |
| 01.17.2025 16:00-20:00 | Grupo /CLE_01 | Classroom 04: James Watson and Francis Crick |
| 06.30.2025 16:00-20:00 | Grupo /CLE_01 | Classroom 03. Carl Linnaeus |